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arXiv:0710.0445q-bio.PE

Evolution of the genetic code from the GC- to the AGUC-alphabet

Denis A. Semenov

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Abstract

A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards point mutations, the presence of code dialects, and the symmetry of the genetic code table.

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DOI
Subjects
q-bio.PEPopulations and Evolution q-bio.BMBiomolecules

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  1. Alien life form ‘is here on Earth’ 1 comment

    • Some biologists have made a case for DNA replication evolving twice, independently: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC148579/pdf/27338... Apparently you can also make a case for the evolution of DNA itself, possibly from a 2-letter alphabet…

      bedigerView on HNParent context

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