From Genotype to Phenotype: polygenic prediction of complex human traits — mentioned by s1artibartfast

Mon, 08 Aug 2022 16:03:30 GMT

> show me someone who can take a genome and predict adult height within a centimeter, then I’ll believe they have a snowball’s chance of predicting something as nuanced and varied as “attractiveness” or “intelligence”. This has been done. Not to 1cm but ~3cm, and it has been reproduced by many labs all over the world That said, most genetic prediction aren't targeting exact vales, but avoiding the worst outcomes, which is a lot easier. Instead of saying this embryo will go grow to X cm, the claim is this embryo is 90% likely to grow to be taller than average. Same for IQ. They don't predict…

Paper and discussion history. A mention is not an endorsement.

From Genotype to Phenotype: polygenic prediction of complex human traits · HackerPapers discussions

From Genotype to Phenotype: polygenic prediction of complex human traits — mentioned by s1artibartfast