A computational insight of the improved nicotine binding with ACE2-SARS-CoV-2 complex with its clinical impact · HackerPapers discussionshttps://hackerpaper.kaipfister.de/p/2004.14943/Collected HN comments and submissions linking this paper.enMon, 02 Nov 2026 11:16:22 GMTA computational insight of the improved nicotine binding with ACE2-SARS-CoV-2 complex with its clinical impact — mentioned by metrokoihttps://news.ycombinator.com/item?id=23854997urn:hackerpapers:mention:2004.14943:23854997Thu, 16 Jul 2020 02:12:21 GMT<p>Smoking decreases the amount of certain enzymes that COVID binds to in order to infect the lungs. Less enzymes means a lesser chance of catching the virus, but if caught, the person will likely have a more severe case due to the decreased lung capability.[0][1] The figures that I have seen previously did show a very significantly decreased risk of catching COVID, and I&#x27;m surprised it hasn&#x27;t been investigated far more. Edit: I had that wrong, it seems nicotine increases ACE2, but also binds with ACE2 decreasing the amount of available enzymes overall that COVID could bind to.[2]…</p><p><a href="https://hackerpaper.kaipfister.de/p/2004.14943/">Paper and discussion history</a>. A mention is not an endorsement.</p>q-bio.BM