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arXiv:1503.01493q-bio.NC

Self-tracking Energy Transfer for Neural Stimulation in Untethered Mice

John S. Ho, Yuji Tanabe, Shrivats Mohan Iyer, Amelia J. Christensen, Logan Grosenick, Karl Deisseroth, Scott L. Delp, Ada S. Y. Poon

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Abstract

Optical or electrical stimulation of neural circuits in mice during natural behavior is an important paradigm for studying brain function. Conventional systems for optogenetics and electrical microstimulation require tethers or large head-mounted devices that disrupt animal behavior. We report a method for wireless powering of small-scale implanted devices based on the strong localization of energy that occurs during resonant interaction between a radio-frequency cavity and intrinsic modes in mice. The system features self-tracking over a wide (16 cm diameter) operational area, and is used to demonstrate wireless activation of cortical neurons with miniaturized stimulators (10 mm$^{3}$, 20 mg) fully implanted under the skin.

arXiv comments
Journal reference
DOI
doi:10.1103/PhysRevApplied.4.024001
Subjects
q-bio.NCNeurons and Cognition physics.ins-detInstrumentation and Detectors physics.opticsOptics

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    • shahryc, thanks for posting (and reposting) this story. It's some fascinating research. The paper in "Physical Review Applied" (linked in article) is paywalled, but there is a pre-print version available here: http://arxiv.org/abs/1503.01493

      jcrView on HNParent context

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