Determination of Nonlinear Genetic Architecture using Compressed Sensing · HackerPapers discussionshttps://hackerpaper.kaipfister.de/p/1408.6583/Collected HN comments and submissions linking this paper.enMon, 02 Nov 2026 11:16:22 GMTDetermination of Nonlinear Genetic Architecture using Compressed Sensing — mentioned by stephenhsuhttps://news.ycombinator.com/item?id=8465790urn:hackerpapers:mention:1408.6583:8465790Thu, 16 Oct 2014 16:30:49 GMT<p>The question of additivity of genetic effects is discussed in more detail in reference [1] above (sections 3.1 and also 4): http://arxiv.org/pdf/1408.3421v2.pdf In plant and animal genetics it is well established that the majority of phenotype variance in complex traits which is under genetic control is additive. (Linear models work well in species ranging from corn to cows; cattle breeding is now done using SNP genotypes and linear models to estimate phenotypes.) There are also direct estimates of the additive / non-additive components of variance for human height and IQ, from twin and…</p><p><a href="https://hackerpaper.kaipfister.de/p/1408.6583/">Paper and discussion history</a>. A mention is not an endorsement.</p>q-bio.GN